An optimization model is introduced in which proteins try to evade high energy regions of the folding landscape. and prefer low entropy loss routes during folding. We make use of the framework of optimal control whose convenient solution provides practical and useful insight into the sequence of events during folding. We assume that the native state is available. https://jalyttlers.shop/product-category/wobbly-bowl/
Prediction of optimal folding routes of proteins that satisfy the principle of lowest entropy loss: dynamic contact maps and optimal control.
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