Abstract Background Poly(ADP-ribose) polymerase-1 (PARP-1) is a pan nuclear protein that utilizes NAD+ as a substrate for poly(ADP-ribosyl)ation reaction (PARylation). resulting in both auto-modification and the modification of its accepter proteins. Earlier reports suggested that several nucleolar proteins interact and colocalize with PARP-1. leading to their PARylation. https://www.diegojavierfares.com/flash-offer-A-D-EJ-123-Newton-Compact-Balance-Scale-120-x-0-001-g-hot-grab/