The adaptive immune system of jawed vertebrates generates a highly diverse repertoire of antibodies to meet the antigenic challenges of a constantly evolving biological ecosystem. Most of the diversity is generated by two mechanisms: V(D)J gene recombination and somatic hypermutation (SHM). SHM introduces changes in the variable domain of antibodies. mostly in the regions that form th... https://www.jmannino.com/mega-pick-Royal-Nomadic-5413-Rug-Ivory-Black-limited-super/